In this talk we will show advancements on the usage of supercomputer-based modelling and simulation in advanced biomedical applications, including tools for creating virtual populations of Virtual Human Twins and “Twinoids”. In particular, we will showcase computational achievements on coupled multi-scale and multi-physics problems to create in-silico clinical trials to understand physiology and to improve old and create new and better therapies. Regarding the application problems, we will present contributions on blood circulatory system, cardiac hemodynamics, bioprosthetic heart valves implants and valve reparation surgical procedures, respiratory fluid mechanics from upper airways down to alveoli, inhalers and nebulizers, lung models, spinal intrathecal fluid mechanics, etc.

About the speaker

Mariano Vázquez is CTO/CSO of the company ELEM Biotech, which develops and commercialises supercomputer-based applications for the biomedical sector, and researcher of the Barcelona Supercomputing Center, from which ELEM spun off in 2018. He has a PhD from the Technical University of Catalunya (UPC) with postdocs in Dassault Aviation and in INRIA Sophia Antipolis in France.