There have been rapid changes in technology and approaches being utilized to bring safer and more effective drugs to the clinic. Despite those efforts, adverse drug events such as cardiotoxicity, hepatotoxicity and other organ toxicities, keep surfacing in the clinic and idiosyncratic drug toxicity continues to haunt the drug development process. So what can scientists do to make sure that the lead compounds are optimized and validated early and accurately to avoid costly mistakes from happening later? Cambridge Healthtech Institute’s inaugural conference on Optimizing Leads and Predicting Drug Toxicity, looks at the scientific and technological progress being made to better optimize drug candidates and accurately predict drug related toxicities, early in drug development. What assays and models are being used, how reliable and predictable is the data, and how is this information translated into knowledge that then impacts decision-making? Hear experiences shared by experts and join the interactive sessions and panel discussions for active networking, brainstorming and collaborating.