Means to achieve this:

• to offer a WG-overarching education/communication/discussion event involving the audience via interactive sessions;

• to layout ways to go beyond with anything the nanosafety community have learned/developed to serve the emerging topics of Horizon Europe (emerging contaminants incl. microplastics, nanomedicine, safety assessment of novel/innovative/advanced materials for tomorrow along their entire life cycle);

• to foster participation in creating better sustainable materials (than e.g. nanosilver in socks), technologies, medical approaches, etc.

• to exhibit the perspectives of the NSC Working Groups and the different currently ongoing projects;

• to be as interactive as possible using hands-on activities, e.g., by showing how-to operate e-tools, upload/retrieve data to/from repositories & perform models;

• to facilitate vivid contribution to discussions using survey tools such as Mentimeter, WooClap, VoxVote, etc.

• to offer different perspectives in pro/contra discussions, e.g., by defining challenger - defender roles taken by experts on specific topics or evtl. by dividing attendees into zoom breakout rooms

• to show application of emerging NRG frameworks or SbD tools;

• to request feedback to user interfaces and enable stakeholder involvement.

Program in CET

9:00-9:05 h Welcome of the day by Martin Himly, PLUS (Chair of NSC WG-A)

Block 1 - Emerging approaches in nanorisk assessment

Session 1: New developments in human hazard assessment - focus on AOP, QSAR, IATA
    9:05-9:15 h (i)  Session intro on “The Why and What and How of AOPs and various emerging approaches – QSAR, NAMs, IATA” by Session Chair Peter Hoet, KathUni Leuven
    9:15-9:30 h (ii) “Beyond chemocentric models: from toxicogenomics to integrated approaches for IATA development” by Dario Greco, Uni Tampere
    9:30-9:45 h (iii) AOPs and data integration within Nanosafety” by Penny Nymark, Karolisnka Institutet
    9:45-10 h (iv) “Showcasing the AOP-Wiki Resource Description Framework – why nano-AOPs do not exist” by Marvin Martens, Uni Maastricht

Short break 10:00-10:05 h

Session 2: Exposure & life cycle assessment - determination & modeling
    10:05 h Introduction of Session Chair Wouter Fransman, TNO
    10:05-10:15 h (i) “Extrapolation (i.e. re-use) of exposure measurement data for similar exposure scenarios and/or similar materials - from regular chemicals to NMs” by Remy Franken, TNO
    10:15-10:30 h (ii) “Sharing of release and exposure measurement data” by Camilla Delpivo, Leitat
    10:30-10:45 h (iii) “Efficiency testing and implementation of risk management measures to mitigate exposure to NMs” by Henk Goede, TNO
    10:45-11:00 h (iv) “Life cycle thinking in nanoform release assessment” by Nathan Bossa, Leitat

Virtual coffee, tea & sweets break 11:00 - 11:05 h

Block 2 – Data workshop & e-tools for nano & beyond

Session 3: Data FAIRness, metadata completeness, scientific quality assurance
    11:05-11:10 h (i) Session intro “Experiences from NanoFASE going FAIR” by Session Chair Claus Svendsen, UKCEH
    11:10-11:35 h (ii) “When is a metadata set complete?” showcasing (a) specific example(s) with discussion moderated by Thomas Exner, Edelweiss Connect
    11:35-12 h (iii) “How to implement (scientific) FAIR principles in my work?” showcasing support in data FAIRness for projects by Ammar Ammar, Uni Maastricht

Short break 12:00-12:05 h

Session 4: Spectrum of e-tools along data life cycle
    12:05-12:15 h (i) Session intro “Data life cycle - generation processing, evaluation, prediction, curation” by Session Chair Iseult Lynch, UoB
    12:15-12:25 h (ii) “Showcasing the NanoCommons exposure/risk assessment tool: http://enaloscloud.novamechanics.com/nanocommons/exposure/” by Periklis Tsiros, Harry Sarimveis, NTUA
    12:25-12:35 (iii) “Showcasing read-across of NM properties (i.e. zeta potential) to cytotoxicity using NanoSolveIT’s and NanoCommons nanoinformatics models:  https://cellviability.cloud.nanosolveit.eu/ and http://enaloscloud.novamechanics.com/nanocommons/mszeta/” by Tassos Papadiamantis, UoB, NovaMechanics, Georgia Melagraki, Antreas Afantitis NovaMechanics
    12:35-12:45 (iv) “Showcasing NanoSolveIT’s human exposure assessment: https://aerosol.cloud.nanosolveit.eu/1/” by Nikolaos Cheimarios, Andreas Tsoumanis, Georgia Melagraki, Antreas Afantitis, NovaMechanics
    12:45-12:55 h (v) “Idea, methodology, current state of the NanoInformaTIX platform” by Gianpetro Basei, Greendecision
    12:55-13:00 h (vi) “Call for action on the Gracious Ontology-Wiki” by Thomas Exner, Edelweiss Connect

Working lunch and NSC General Assembly 13:00 – 14:30 h

Virtual coffee, tea & sweets break 14:30 – 14:45 h

Block 3 - NanoRisk Governance & Safe-by-Design concepts - fit for translation to sustainable development?

Session 5: Features of nanoRGFs in development & current NRGC concepts
    14:45-14:55 h (i) “What do we need a NRG Council for, who are its stakeholders and what are their needs?” by Marie-Valentin Florin, NanoRigo
    14:55-15:05 h (ii) “What can we expect from a future NRG Council and what is the current view on its design” by Rob Aitken, Gov4Nano
    15:05-15:25 h (iii) “Screening ethical issues for governance of nanorisk: http://enaloscloud.novamechanics.com/riskgone/thresholdanalysis/” by Ineke Malsh, RiskGone
    15:25-15:45 h (iv) “Insight into the nanorisk governance process guided by the NanoRigo NRG framework” by Arto Säämänen, and “Requirements on NRG frameworks by insurances and other societal stakeholders” by Martin Mullins, NanoRigo

Short break 15:45-15:50 h

Session 6: Elements of SbD for sustainable development & innovation
    15:50-15:55 h (i) Session intro “SbD - from philosophy to application” by Session Chair Andrew Nelson (SABYDOMA)
    15:55-16:10 h (ii) “Elevator pitches by other 3 NMBP-15 projects” by Soco Vazquez (SABYNA), Carlos Fito (SbD4Nano), Anna Costa (ASINA)
    16:10-16:20 h (iii) “Presenting two case studies (CS) to apply different SbD concepts: (a) CS1 on SbD for Covid-19: antiviral coating, strategies for pharma” by Anna Costa; arising questions for SbD application in CS1
    16:20-16:30 h (b) “CS2 on SbD in plastics/3D printing/additive manufacturing” by Soco Vazquez; arising questions for SbD applications in CS2
    16:30-16:45 h (iv) General discussion of views/feelings moderated by Susanne Resch, BNN, for CS1 and Soco Vazquez, Leitat, for CS2
    16:45-16:50 h (v) Session summary & outlook to green innovation jointly by Andrew Nelson and Martin Himly

Virtual refreshments, coffee, tea & sweets break 16:50 - 17:00 h

The focus of the sessions will be on gains to the entire process, explaining how the tools fit into the wider strategy and what remains after the projects have finished, where to find further info to get things applied in users’ own hands.